Author Topic: d aspartic acid  (Read 9627 times)

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fast does lie

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d aspartic acid
« on: December 19, 2012, 02:22:56 pm »
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It's suppose to aid in muscle growth and recovery by increase of growth hormones and test.  Could some nutrition guru's chime in?  And what's this i hear about it also increasing estrogen while it increases test?  and therefore you would need an aromatase blocker along with it if you're goign to take it.

confused.
33yrs | 24in SVJ | >45% BF | 227LB | 5'9 | 7'5 reach | 400lb max squat paused | 5'8 wingspan | 26in RVJ

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LBSS

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Re: d aspartic acid
« Reply #1 on: December 19, 2012, 02:37:06 pm »
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what you've heard/read is probably voodoo. you probably get all the aspartic acid you need from your diet. any supplemental probably has at best a small effect. and i hate to break it to you, but the people for whom this (and lots of other boutique dietary supplements) might have an actual training effect are light years ahead of you or me or most of the dudes on here.

only abstract i could find, which doesn't exactly inspire confidence:

Quote
Reprod Biol Endocrinol. 2009 Oct 27;7:120. doi: 10.1186/1477-7827-7-120.
The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.
Topo E, Soricelli A, D'Aniello A, Ronsini S, D'Aniello G.
Source

1Stazione Zoologica Anton Dohrn, 80121, Villa Comunale, 80121, Napoli, Italy. enza.topo@szn.it
Abstract
BACKGROUND:

D-aspartic acid is an amino acid present in neuroendocrine tissues of invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this amino acid on the release of LH and testosterone in the serum of humans and rats. Furthermore, we investigated the role of D-aspartate in the synthesis of LH and testosterone in the pituitary and testes of rats, and the molecular mechanisms by which this amino acid triggers its action.
METHODS:

For humans: A group of 23 men were given a daily dose of D-aspartate (DADAVIT) for 12 days, whereas another group of 20 men were given a placebo. For rats: A group of 10 rats drank a solution of either 20 mM D-aspartate or a placebo for 12 days. Then LH and testosterone accumulation was determined in the serum and D-aspartate accumulation in tissues. The effects of D-aspartate on the synthesis of LH and testosterone were gauged on isolated rat pituitary and Leydig cells. Tissues were incubated with D-aspartate, and then the concentration (synthesis) of LH and cGMP in the pituitary and of testosterone and cAMP in the Leydig cells was determined.
RESULTS:

In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release. In the rat pituitary, sodium D-aspartate increases the release and synthesis of LH through the involvement of cGMP as a second messenger, whereas in rat testis Leydig cells, it increases the synthesis and release of testosterone and cAMP is implicated as second messenger. In the pituitary and in testes D-Asp is synthesized by a D-aspartate racemase which convert L-Asp into D-Asp. The pituitary and testes possesses a high capacity to trapping circulating D-Asp from hexogen or endogen sources.
CONCLUSION:

D-aspartic acid is a physiological amino acid occurring principally in the pituitary gland and testes and has a role in the regulation of the release and synthesis of LH and testosterone in humans and rats.
Muscles are nonsensical they have nothing to do with this bullshit.

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LBSS

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Re: d aspartic acid
« Reply #2 on: December 19, 2012, 03:21:17 pm »
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Quote
In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release

That statement seems positive.

so?
Muscles are nonsensical they have nothing to do with this bullshit.

- Avishek

https://www.savannahstate.edu/cost/nrotc/documents/Inform2010-thearmstrongworkout_Enclosure15_5-2-10.pdf

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pelham32

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Re: d aspartic acid
« Reply #3 on: December 21, 2012, 01:38:25 pm »
+1
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Hodge twins review
« Last Edit: December 21, 2012, 01:40:03 pm by pelham32 »
Goal

windmill consistently/ touch top of the square consistently



weight= 193
height= 6'3 1/2
highest touch= top of the square, which is 11'4