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Performance Area => Nutrition & Supplementation => Topic started by: ghettoracer on March 19, 2016, 10:14:29 am

Title: glycine
Post by: ghettoracer on March 19, 2016, 10:14:29 am
i was looking around on Kelly Baggett's site and came across him saying he felt taking glycine was more effective than taking glucosamine - http://www.higher-faster-sports.com/bestsupplementforjointhealth.html

personally i used to take glucosamine but playing lots of basketball 4-5 years ago (2-3 hours daily, 3-3 and full court) i physically felt zero difference once i stop taking multivitamins and glucosamine all together.  the only difference was i stop peeing yellow.  now that i'm few years older and entering into 40's now i'm a bit more cautious.  on the plus side glycine is cheap to buy here in Taiwan.  it is sold as a food grade additive (sweetener).  made by Japan's Showa Denko 1kg shipped is only 410nt or ~$13.  i plan to try some and report back the results.  a quick search on this site only turn up a handful of post about it and not much discussion.

i took a quick look at couple of google results and it seems like a good supplement:

https://en.wikipedia.org/wiki/Glycine
http://www.webmd.com/vitamins-supplements/ingredientmono-1072-glycine.aspx?activeingredientid=1072&activeingredientname=glycine
https://examine.com/supplements/glycine/

from these sources, they all seem to indicate glycine as positive and with no drawbacks.  summary:

Quote
Glycine is an amino acid, a building block for protein. It is not considered an “essential amino acid” because the body can make it from other chemicals. A typical diet contains about 2 grams of glycine daily. The primary sources are protein-rich foods including meat, fish, dairy, and legumes.

Glycine is used for treating schizophrenia, stroke, benign prostatic hyperplasia (BPH), and some rare inherited metabolic disorders. It is also used to protect kidneys from the harmful side effects of certain drugs used after organ transplantation as well as the liver from harmful effects of alcohol. Other uses include cancer prevention and memory enhancement.

Some people apply glycine directly to the skin to treat leg ulcers and heal other wounds.

How does it work?
The body uses glycine to make proteins. Glycine is also involved in the transmission of chemical signals in the brain, so there is interest in trying it for schizophrenia and improving memory. Some researchers think glycine may have a role in cancer prevention because it seems to interfere with the blood supply needed by certain tumors.
Title: Re: glycine
Post by: ghettoracer on March 19, 2016, 10:47:12 am
amazon reviews:

http://www.amazon.com/NOW-Foods-Glycine-1-Pound/dp/B0013OVZJW

http://www.amazon.com/BulkSupplements-Pure-Glycine-Powder-Kilogram/dp/B00EOXU0MM

another pro-glycine article:

http://www.theguthealthprotocol.com/wp/glycine-the-most-important-inflammation-regulator/
Title: Re: glycine
Post by: ChrisM on March 19, 2016, 11:47:11 am
I take Glycine... probably a placebo but it seems to be better for my knees than glucosamine.
Title: Re: glycine
Post by: ghettoracer on March 19, 2016, 12:13:45 pm
how much are you taking?
Title: Re: glycine
Post by: ChrisM on March 19, 2016, 10:36:10 pm
2g a day. Just read the bottle....supposed to take 3g lol
Title: Re: glycine
Post by: ghettoracer on March 20, 2016, 02:03:05 am
most ppl seem to take 3g right before they sleep and sleep quality goes up a bit.  many also report general moods being better if taken during the day.  do you feel those effects?
Title: Re: glycine
Post by: LBSS on March 20, 2016, 10:12:28 am
it's just soy. the only thing where it has strong evidence of benefit is reducing cholesterol. so if you're worried about that, carry on. if not then waste your money on something else.

http://www.mayoclinic.org/drugs-supplements/soy/evidence/hrb-20060012
Title: Re: glycine
Post by: AGC on March 20, 2016, 06:50:45 pm
it's just soy. the only thing where it has strong evidence of benefit is reducing cholesterol. so if you're worried about that, carry on. if not then waste your money on something else.

http://www.mayoclinic.org/drugs-supplements/soy/evidence/hrb-20060012

Unless I'm mistaken, these guys are talking about pure glycine. Soybean is certainly not 100% glycine, more like 2% w/w. Maybe the name has confused you?
Title: Re: glycine
Post by: LBSS on March 20, 2016, 10:41:52 pm
it's just soy. the only thing where it has strong evidence of benefit is reducing cholesterol. so if you're worried about that, carry on. if not then waste your money on something else.

http://www.mayoclinic.org/drugs-supplements/soy/evidence/hrb-20060012

Unless I'm mistaken, these guys are talking about pure glycine. Soybean is certainly not 100% glycine, more like 2% w/w. Maybe the name has confused you?

yeah obviously soy is not 100% glycine, but that article is what comes up when you search for glycine on mayoclinic. the subtitle is "Glycine max," whatever that means.

dunno.
Title: Re: glycine
Post by: AGC on March 21, 2016, 01:00:36 am
it's just soy. the only thing where it has strong evidence of benefit is reducing cholesterol. so if you're worried about that, carry on. if not then waste your money on something else.

http://www.mayoclinic.org/drugs-supplements/soy/evidence/hrb-20060012

Unless I'm mistaken, these guys are talking about pure glycine. Soybean is certainly not 100% glycine, more like 2% w/w. Maybe the name has confused you?

yeah obviously soy is not 100% glycine, but that article is what comes up when you search for glycine on mayoclinic. the subtitle is "Glycine max," whatever that means.

dunno.

Yeah that's the scientific name for soybean. As far as I can tell, it has absolutely nothing to do with the amino acid glycine ¯\_(ツ)_/¯
Title: Re: glycine
Post by: LBSS on March 21, 2016, 07:22:19 am
ah so, my mistake.
Title: Re: glycine
Post by: ghettoracer on March 27, 2016, 02:41:42 pm
okay i've taken ~5 grams of glycine right before i sleep for 3 nights in a row now.  another 5 grams during the day.  i can't say i feel much more refreshed when i wake up.  however, i can tell you for sure i am dreaming a lot more and they are more vivid.  certainly that could mean deeper sleep than usual.  just about an hour ago i had a clear vivid dream that i was having an out of body experience.  like, i was able to instantly lay down and fall asleep right away.  but i would sit up and be "out of body" right away.  kind of hard to explain but it took lot of effort to "get up".  have you guys ever have the experience of trying to keep awake when you're super tired and falling asleep (or is already sleeping) and your eye lids feels like they weights a ton.  well that's the feeling when i was trying to get up except it's not just the eyes lids that felt heavy, but the entire body felt heavy until you "break from it".  it felt very real...  but as i try to turn around and look at my physical body i wasn't able to see my self clearly at all.  then i realized i was dreaming.  pretty neat experience.  i woke up not long after so i was able to recall it clearly.

as for glycine's other effects i'll have to observe more.

it looks and taste like sugar even down to water solubility.  first time i mix it with 2-3 oz of water but it wouldn't completely dissolve so now i just put i on my tongue and wash it down with water.